LEO Pharma Open Innovation

Participate as an Academic Researcher

The information below is intended for academic researchers including (but not limited to) university-employed post-docs, research group leaders, professors, or any other university-associated scientist.

LEO Pharma Open Innovation – the background

Our mission is to help people achieve healthy skin, and to do that we need to explore the science behind diseases such as eczema and psoriasis, as well as new treatment options. LEO Pharma Open Innovation allows researchers to submit molecules to be tested for biological effects in advanced cell-based and disease-relevant in vitro assays. You can read more about the science behind the diseases and assays here.

In this early stage of research and collaboration we would like to focus on the science and will therefore make no claims or ask for anything in return for testing your molecules (which remain confidential) – just that we can evaluate their effects and, if we both agree that they are interesting, discuss a continued collaboration. The results that we generate from testing your molecules will be owned by you. This means that you are free to publish them, use them in a grant application or pursue any direction you decide to.

We would like to explore science that can help in identifying new

  1. disease-relevant biological pathways,
  2. targets for treatment, and
  3. molecules that can be developed further

 

How to participate and explore science together

We’d love to test your molecules that you have worked on and developed. They could be hits in a relevant assay, optimised leads with a specific biological effect, tool compounds or chemical probes. Knowing the details of the assays we will test your molecules in you are able to identify opportunities where your molecules and ideas might be relevant. If you believe that that the mechanism which your molecules work by is relevant for some of the assays provided we really want to explore that scientific possibility.

Submitting molecules for testing

Submitting molecules is a simple process.

  1. You download the agreement (which will make no claims to your molecules), fill out your affiliation, a nominal name of the molecules and molecular weight. Have your legal representative sign, scan and send to us by email.
  2. We will counter-sign the contract and send you vials for shipping the molecules.
  3. You return the vials with your molecules to be tested.
  4. We will schedule testing and return all data generated upon completion.

 

Data for publications

The data that we jointly generate using your molecules and our biological assays are owned by you and therefore it is up to you if you want to keep them confidential or make them publicly available. In general, if you are looking for business opportunity you should keep the molecular structure a secret. But if that’s not what you’re looking for we strongly recommend sharing the results, so that they can have a broader impact on science and finding new collaborative opportunities. In this case both positive and negative results are important to share.

 

Funding or other support

In the first step, LEO Pharma Open Innovation provides support in the form of in-kind research contributions by providing access to advanced biological research tools in a pharmaceutical setting. In addition, it is possible to collaborate with LEO Pharma as an industry partner when applying for other research grants. Please contact us if you plan to submit a grant application that overlaps with our disease and scientific interest as we might be able to assist with in-kind contributions using the open innovation platform and provide a non-committal possibility for extended collaborations. Furthermore, if the results from the initial open innovation testing are interesting we could propose a follow-up study where we will commit more and/or alternative resources to further investigate the functional relevance of your molecule(s). Occasionally, after positive results, we can provide enabling funding to a limited extent in order to support a specific task, for example third party testing of molecules in order to generate data necessary to evaluate the opportunity.